This thesis focuses on the development of a gold nanoparticle biosensor for the detection, identification, and quantification of proteins.
This method involves transferring metal cations from the aqueous layer to the organic one by the phase transfer reagent, tetraoctylammonium bromide, followed by reduction with sodium borohydride in the presence of oleylamine, which was used as the stabilising ligand. Among nanoparticles, gold nanoparticles demonstrate special advantages in this field due to their unique properties, small size and high surface area-to-volume ratio. Characterization techniques for nanoparticles: comparison and complementarity upon studying nanoparticle properties Stefanos Mourdikoudis, a,b Roger M. Pallares a,b and Nguyen T. K. Thanh *a,b Nanostructures have attracted huge interest as a rapidly growing class of materials for many applications. Nanoparticles.
i “Science is a difficult field that demands great effort and dedication, but if you are willing to make the effort, there is much to gain.” George William Gray . This thesis study focuses on synthesizing and characterizing gold-magnetite optically active magnetic nanoparticle and its conjugation with biomolecules for biomedical applications, especially magnetic fluid hyperthermia treatment for cancerous tissue. In Part II of this PhD thesis the experimental results and discussions are given. able colors of gold and silver nanoparticles in solution. The underlying principle is based on the aggregation of non-functionalized gold nanoparticles in the presence of proteins. In nanotechnology, a particle is defined as a small object that behaves as a whole unit with respect to its transport and properties. This review introduces the field of nanotechnology with a focus on recent gold nanoparticle research which has led to early-phase clinical trials. Gold Nanoparticles being a Thesis submitted for the Degree of Doctor of Philosophy in the University of Hull by BaiJia Tang MChem (Hons) MRSC December 2013 . Gold nanoparticles are emerging as promising agents for cancer therapy and are being investigated as drug carriers, photothermal agents, contrast agents and radiosensitisers.
Particles are further classified according to diameter. View Gold Nanoparticles Research Papers on Academia.edu for free. These particles have been widely used in various biomedical applications and drug delivery systems due to their inert nature, stability, high dispersity, non-cytotoxicity and biocompatibility.
The physicochemical characteristics of these gold nanoparticles can be manipulated to alter their response to different proteins. Different wet chemical synthesis techniques to fabricate gold nanoparticles are ex-plained in Chapter 3, focussing on introducing chirality in the synthesis methods. Nanoparticles are particles between 1 and 100 nanometers in size. Gold nanoparticles have already displayed their potential in the biomedical field. fabrication of alkylamine-capped gold nanoparticles.
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